Supervisor: Prof. dr. P.A.W.H. Kessler Co-supervisors: Dr. C.M. Speksnijder (UMCU) Dr. F.J. Hoebers Assessment Committee: Prof. dr. P.M. Steijlen (Chair) Prof. dr. M.A.W. Merkx (Radboudumc) Prof. dr. E.J.M. Speel Prof. dr. V. Tjan-Heijnen Prof. dr. A. Visser (UMCG)
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