Mehmet Nizamoglu

108 Chapter 4 167. Nizamoglu M, Burgess JK. The Multi-Faceted Extracellular Matrix: Unlocking Its Secrets for Understanding the Perpetuation of Lung Fibrosis. Curr Tissue Microenviron Rep 2022: 2(4): 53-71. 168. Junior C, Narciso M, Marhuenda E, Almendros I, Farre R, Navajas D, Otero J, Gavara N. Baseline Stiffness Modulates the Non-Linear Response to Stretch of the Extracellular Matrix in Pulmonary Fibrosis. Int J Mol Sci 2021: 22(23): 12928. 169. Reimelt AM, Vasilescu DM, Beare R, Knudsen L, Grothausmann R. 3D image analysis of the alveolar shape in human lungs. Eur Respir J 2021: 58(suppl 65): PA1876. 170. Barnes PJ, Bonini S, Seeger W, Belvisi MG, Ward B, Holmes A. Barriers to new drug development in respiratory disease. Eur Respir J 2015: 45(5): 1197-1207. 171. Yamaguchi S, Kaneko M, Narukawa M. Approval success rates of drug candidates based on target, action, modality, application, and their combinations. Clin Transl Sci 2021: 14(3): 1113-1122. 172. Cook D, Brown D, Alexander R, March R, Morgan P, Satterthwaite G, Pangalos MN. Lessons learned from the fate of AstraZeneca’s drug pipeline: a fivedimensional framework. Nature Rev Drug Discov 2014: 13(6): 419-431. 173. Sgalla G, Lerede M, Richeldi L. Emerging drugs for the treatment of idiopathic pulmonary fibrosis: 2020 phase II clinical trials. Expert Opin Emerg Drugs 2021: 26(2): 93-101. 174. Wilson JW, Li X, Pain MC. The lack of distensibility of asthmatic airways. Am Rev Respir Dis 1993: 148(3): 806-809. 175. Ward JE, Harris T, Bamford T, Mast A, Pain MCF, Robertson C, Smallwood D, Tran T, Wilson J, Stewart AG. Proliferation is not increased in airway myofibroblasts isolated from asthmatics. Eur Respir J 2008: 32(2): 362-371. 176. Chapman DG, King GG, Berend N, Diba C, Salome CM. Avoiding deep inspirations increases the maximal response to methacholine without altering sensitivity in non-asthmatics. Respir Physiol Neurobiol 2010: 173(2): 157-163. 177. Tschumperlin DJ, Dai G, Maly IV, Kikuchi T, Laiho LH, McVittie AK, Haley KJ, Lilly CM, So PT, Lauffenburger DA, Kamm RD, Drazen JM. Mechanotransduction through growthfactor shedding into the extracellular space. Nature 2004: 429(6987): 83-86. 178. Park JA, Tschumperlin DJ. Chronic intermittent mechanical stress increases MUC5AC protein expression. Am J Respir Cell Mol Biol 2009: 41(4): 459-466. 179. Stewart AG, Thomas B, Koff J. TGF-beta: Master regulator of inflammation and fibrosis. Respirology 2018: 23(12): 10961097. 180. Liu G, Cooley MA, Jarnicki AG, Borghuis T, Nair PM, Tjin G, Hsu AC, Haw TJ, Fricker M, Harrison CL, Jones B, Hansbro NG, Wark PA, Horvat JC, Argraves WS, Oliver BG, Knight DA, Burgess JK, Hansbro PM. Fibulin-1c regulates transforming growth factor-beta activation in pulmonary tissue fibrosis. JCI Insight 2019: 5(16).

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