The studies presented in this thesis were performed within an industrial collaborative PhD program between University Medical Center Groningen (UMCG) and Boehringer Ingelheim. The printing of this thesis was financially supported by the University of Groningen, Graduate School of Medical Sciences, the Dutch Society for Matrix Biology (NVMB) and Boehringer Ingelheim. ISBN (printed): 978-94-6483-345-4 Cover design: Albano Tosato Layout: Wouter Aalberts | www.persoonlijkproefschrift.nl Print: Ridderprint | www.ridderprint.nl © Mehmet Nizamoglu, 2023 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means without the permission of the author, or when applicable, from the editorial publishers.
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