251 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 7: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for mean intensity of weakly stained PicroSirius Red on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.600 0.663 0.071 Control Fb 0.600 0.181 IPF Fb 0.663 0.181 IPF Hydrogels Empty 0.071 0.682 0.026 Control Fb 0.682 0.062 IPF Fb 0.026 0.062 Not significant Significant Comparison not applicable Supplementary Figure 9: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of mean intensity of weakly stained PicroSirius Red (PSR) area (au) for day 7 samples. 9
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