257 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 13: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for weakly stained Alcian Blue area on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.281 0.080 0.696 Control Fb 0.281 0.453 IPF Fb 0.080 0.453 IPF Hydrogels Empty 0.696 1.000 0.827 Control Fb 1.000 0.827 IPF Fb 0.827 0.827 Not significant Significant Comparison not applicable Supplementary Figure 15: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of weakly stained Alcian blue (AB) area (%) for day 7 samples. 9
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