259 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 15: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for moderately stained Alcian Blue area on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.234 0.064 0.430 Control Fb 0.234 0.456 IPF Fb 0.064 0.456 IPF Hydrogels Empty 0.430 0.780 0.871 Control Fb 0.780 0.906 IPF Fb 0.871 0.906 Not significant Significant Comparison not applicable Supplementary Figure 17: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of moderately stained Alcian blue (AB) area (%) for day 7 samples. 9
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