261 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 17: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for strongly stained Alcian Blue area on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.507 0.201 0.488 Control Fb 0.507 0.505 IPF Fb 0.201 0.505 IPF Hydrogels Empty 0.488 0.463 0.240 Control Fb 0.463 0.650 IPF Fb 0.240 0.650 Not significant Significant Comparison not applicable Supplementary Figure 19: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of strongly stained Alcian blue (AB) area (%) for day 7 samples. 9
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