263 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 19: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for high-density matrix on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.400 0.412 0.630 Control Fb 0.400 0.109 IPF Fb 0.412 0.109 IPF Hydrogels Empty 0.630 0.147 0.631 Control Fb 0.147 0.362 IPF Fb 0.631 0.362 Not significant Significant Comparison not applicable Supplementary Figure 21: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of percentages of high-density matrix (%) for day 7 samples. 9
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