265 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 21: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for fiber alignment on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.266 0.401 0.572 Control Fb 0.266 0.844 IPF Fb 0.401 0.844 IPF Hydrogels Empty 0.572 0.366 0.094 Control Fb 0.366 0.013 IPF Fb 0.094 0.013 Not significant Significant Comparison not applicable Supplementary Figure 23: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of percentages of alignment (%) for day 7 samples. 9
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