267 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 23: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for average fiber length on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.311 0.689 0.004 Control Fb 0.311 0.175 IPF Fb 0.689 0.175 IPF Hydrogels Empty 0.004 0.137 0.802 Control Fb 0.137 0.240 IPF Fb 0.802 0.240 Not significant Significant Comparison not applicable Supplementary Figure 25: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of average fiber length (μm) for day 7 samples. 9
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