275 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 31: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for high curvature window on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.857 0.511 0.460 Control Fb 0.857 0.610 IPF Fb 0.511 0.610 IPF Hydrogels Empty 0.460 0.345 0.171 Control Fb 0.345 0.025 IPF Fb 0.171 0.025 Not significant Significant Comparison not applicable Supplementary Figure 33: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of curvature of fibers in high curvature windows (°) for day 7 samples. 9
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