279 Fibroblast remodeling of extracellular matrix is directed by the fibrotic nature of the threedimensional microenvironment Supplementary Table 35: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for time to reach 50% stress relaxation on day 7 samples Control Hydrogels IPF Hydrogels Empty Control Fb IPF Fb Empty Control Fb IPF Fb Control Hydrogels Empty 0.745 0.821 1.47 x 10-¹² Control Fb 0.745 0.924 IPF Fb 0.821 0.924 IPF Hydrogels Empty 1.47 x 10-¹² 0.573 0.691 Control Fb 0.573 0.358 IPF Fb 0.691 0.358 Not significant Significant Comparison not applicable Supplementary Figure 37: Individual comparisons between the different groups of empty and fibroblast-seeded control and IPF hydrogels for the estimates of time to reach 50% stress relaxation (s) for day 7 samples. 9
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