Mehmet Nizamoglu

44 Chapter 2 15. McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, AbdalaValencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging. J Clin Invest 2021: 131(4). 16. Blokland KEC, Pouwels SD, Schuliga M, Knight DA, Burgess JK. Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases. Clin Sci 2020: 134(20): 2681-2706. 17. Vasse GF, Nizamoglu M, Heijink IH, Schleputz M, van Rijn P, Thomas MJ, Burgess JK, Melgert BN. Macrophage-stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives. J Pathol 2021: 254(4): 344-357. 18. Adams TS, Schupp JC, Poli S, Ayaub EA, Neumark N, Ahangari F, Chu SG, Raby BA, DeIuliis G, Januszyk M, Duan Q, Arnett HA, Siddiqui A, Washko GR, Homer R, Yan X, Rosas IO, Kaminski N. Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis. Sci Adv 2020: 6(28): eaba1983. 19. Habermann AC, Gutierrez AJ, Bui LT, Yahn SL, Winters NI, Calvi CL, Peter L, Chung MI, Taylor CJ, Jetter C, Raju L, Roberson J, Ding G, Wood L, Sucre JMS, Richmond BW, Serezani AP, McDonnell WJ, Mallal SB, Bacchetta MJ, Loyd JE, Shaver CM, Ware LB, Bremner R, Walia R, Blackwell TS, Banovich NE, Kropski JA. Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis. Sci Adv 2020: 6(28): eaba1972. 20. Tsukui T, Sun KH, Wetter JB, Wilson-Kanamori JR, Hazelwood LA, Henderson NC, Adams TS, Schupp JC, Poli SD, Rosas IO, Kaminski N, Matthay MA, Wolters PJ, Sheppard D. Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis. Nat Commun 2020: 11(1): 1920. 21. Valenzi E, Bulik M, Tabib T, Morse C, Sembrat J, Trejo Bittar H, Rojas M, Lafyatis R. Singlecell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosisassociated interstitial lung disease. Ann Rheum Dis 2019: 78(10): 1379-1387. 22. Sacher F, Feregrino C, Tschopp P, Ewald CY. Extracellular matrix gene expression signatures as cell type and cell state identifiers. bioRxiv 2021: 2021.2003.2011.434939. 23. Germanguz I, Aranda E, Xiong JC, Kissel N, Nichols A, Gadee E, O’Neill JD. Fibrotic human lung extracellular matrix as a diseasespecific substrate for 3D in-vitro models of pulmonary fibrosis. J Respir Med Lung Dis 2019: 4(1): 1-11. 24. Elowsson Rendin L, Lofdahl A, Ahrman E, Muller C, Notermans T, Michalikova B, Rosmark O, Zhou XH, Dellgren G, Silverborn M, Bjermer L, Malmstrom A, LarssonCallerfelt AK, Isaksson H, Malmstrom J, Westergren-Thorsson G. Matrisome Properties of Scaffolds Direct Fibroblasts in Idiopathic Pulmonary Fibrosis. Int J Mol Sci 2019: 20(16).

RkJQdWJsaXNoZXIy MTk4NDMw