Mehmet Nizamoglu

87 Innovative 3D models for understanding mechanisms underlying lung diseases: powerful tools for translational research agreements such as minimum information about a microarray experiment (MIAME) [137], Animal Research: Reporting of in vivo Experiments (ARRIVE) [138], and the FDA Modernization Act 2.0 [139] provide guidelines intended to improve quality and reproducibility of scientific reports involving microarrays, animal research, and alternative methods used to test drug safety and effectiveness. These agreements are advanced to ensure unified evaluation and interpretation of results and better reproducibility of experiments, moving towards new standards for certifying new methodologies for drug development. Such initiatives could subsequently be moved forward by engaging with reviewers about what to look out for when presented with manuscripts reporting such methodologies, as well as providing information for the research community. Together with a scientific community working harmoniously, reviewers and editors of journals paying attention and looking to apply such standards would greatly benefit the advancements made in generating and using innovative in vitro models for translational research [140, 141]. 4

RkJQdWJsaXNoZXIy MTk4NDMw