94 Chapter 4 platform characterizations of different in vitro models have great potential in furthering our understanding of how altered biochemical and mechanical conditions in lung disease impact cellular behaviour in the 3D environment. • New Approach Methodologies (NAMs) for in vitro models are required to increase the preclinical confidence in these models. Acknowledgements: MMJ is funded by the Graduate School of Medical Sciences of the University of Groningen. MN and JKB receive unrestricted research funds from Boehringer Ingelheim. JKB also acknowledges support from the Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) (Aspasia 015.013.010). AKLC acknowledges support from the Swedish Heart Lung Foundation (grant 20210382). LvO and OG thank the H2020 ITN network EUROoC, project Nr.812954 for its financial support. RF acknowledges partial support from the Spanish Ministry of Science and Innovation (PID2020-113910RB-I00-AEI/10.13039/501100011033). JO acknowledges partial support from the Spanish Ministry of Science and Innovation (PGC2018-097323A-I00).
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