Mehmet Nizamoglu

95 Innovative 3D models for understanding mechanisms underlying lung diseases: powerful tools for translational research REFERENCES 1. Labaki WW, Han MK. Chronic respiratory diseases: a global view. Lancet Respir Med 2020: 8(6): 531-533. 2. Melo-Narvaez MC, Stegmayr J, Wagner DE, Lehmann M. Lung regeneration: implications of the diseased niche and ageing. Eur Respir Rev 2020: 29(157). 3. Hough KP, Curtiss ML, Blain TJ, Liu RM, Trevor J, Deshane JS, Thannickal VJ. Airway Remodeling in Asthma. Front Med 2020: 7: 191. 4. Zhou-Suckow Z, Duerr J, Hagner M, Agrawal R, Mall MA. Airway mucus, inflammation and remodeling: emerging links in the pathogenesis of chronic lung diseases. Cell Tissue Res 2017: 367(3): 537-550. 5. Khedoe P, Wu X, Gosens R, Hiemstra PS. Repairing damaged lungs using regenerative therapy. Curr Opin Pharmacol 2021: 59: 85-94. 6. Petersen TH, Calle EA, Niklason LE. Strategies for lung regeneration. Mater Today 2011: 14(5): 196-201. 7. van der Mark SC, Hoek RAS, Hellemons ME. Developments in lung transplantation over the past decade. Eur Respir Rev 2020: 29(157): 190132. 8. Miller AJ, Spence JR. In Vitro Models to Study Human Lung Development, Disease and Homeostasis. Physiology (Bethesda) 2017: 32(3): 246-260. 9. Burgess JK, Harmsen MC. Chronic lung diseases: entangled in extracellular matrix. Eur Respir Rev 2022: 31(163): 210202. 10. Moreira A, Muller M, Costa PF, Kohl Y. Advanced In Vitro Lung Models for Drug and Toxicity Screening: The Promising Role of Induced Pluripotent Stem Cells. Adv Bio (Weinh) 2022: 6(2): e2101139. 11. Sanderson MJ. Exploring lung physiology in health and disease with lung slices. Pulm Pharmacol Ther 2011: 24(5): 452-465. 12. Liu G, Betts C, Cunoosamy DM, Aberg PM, Hornberg JJ, Sivars KB, Cohen TS. Use of precision cut lung slices as a translational model for the study of lung biology. Respir Res 2019: 20(1): 162. 13. Dandurand RJ, Wang CG, Phillips NC, Eidelman DH. Responsiveness of individual airways to methacholine in adult rat lung explants. J Appl Physiol 1993: 75(1): 364-372. 14. Voabil P, de Bruijn M, Roelofsen LM, Hendriks SH, Brokamp S, van den Braber M, Broeks A, Sanders J, Herzig P, Zippelius A, Blank CU, Hartemink KJ, Monkhorst K, Haanen J, Schumacher TN, Thommen DS. An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer. Nat Med 2021: 27(7): 1250-1261. 15. Martin C, Uhlig S, Ullrich V. Videomicroscopy of methacholine-induced contraction of individual airways in precision-cut lung slices. Eur Respir J 1996: 9(12): 2479-2487. 16. Bergner A, Sanderson MJ. Acetylcholineinduced calcium signaling and contraction of airway smooth muscle cells in lung slices. J Gen Physiol 2002: 119(2): 187-198. 17. Delmotte P, Sanderson MJ. Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices. Am J Respir Cell Mol Biol 2006: 35(1): 110-117. 4

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