GENOME-WIDE ANALYSIS OF 102,084 MIGRAINE CASES IDENTIFIES 123 RISK LOCI AND SUBTYPE-SPECIFIC RISK ALLELES 183 8 Acknowledgements: We thank the study participants for their contribution to this research. We also thank the numerous individuals who contributed to sample collection, storage, handling, phenotyping and genotyping for each of the individual cohorts. We acknowledge the participants and investigators of the FinnGen study. This research has been conducted using the UK Biobank Resource under Application Number 22627.We are supported by following grants: the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH) (grant numbers R21NS09296 and R21NS104398 (D.I.C.)), the Finnish innovation fund Sitra and Finska Läkaresällskapet (E.W.), the Academy of Finland (grant nos. 288509, 312076, 336825 (M.P.)), the Sigrid Juselius Foundation (M.P. and S.R.), the Academy of Finland Center of Excellence in Complex Disease Genetics (grant no. 312062 (S.R.)), the Finnish Foundation for Cardiovascular Research (S.R.), University of Helsinki HiLIFE Fellow and Grand Challenge grants (S.R.), The Novo Nordisk Foundation (NNF14CC0001 and NNF17OC0027594 (T.F.H. and K.B.)), CANDY foundation (CEHEAD) (T.F.H.), and the South-Eastern Norway Regional Health Authority (grant no. 2020034 (B.S.W.)). A list of study-specific acknowledgements and funding information can be found in the Supplementary Note. Author's contributions: H.S., A.M.J.M.v.d.M., T.F.H. and M.P. conceived the study. H.H., B.S.W., S.E.R., G.B., A.V.E.H., L.J.A.K., L.F.T., R.N. and L.S.V. performed analyses in their respective cohorts. K. Hveem, H.S., K.S., A.M.J.M.v.d.M., T.F.H., S.R., J.-A.Z. and M.P. supervised analyses in their respective cohorts. H.H., B.S.W., D.I.C., D.R.N., A.M.J.M.v.d.M., T.F.H., J.-A.Z., A.P. and M.P. contributed to writing the manuscript. H.H. performed metaanalysis, and created figures and tables. H.H. and M.P. performed downstream analyses and drafted the manuscript. M.P. supervised project. All authors interpreted the results and reviewed and commented on the manuscript.
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