9 CHAPTER 9 204 and Teva, Lundbeck and independent support from Dutch Research Council, the Dutch Heart & Brain Foundations, IRRF and Dioraphte. AMJMvdM reports research support from Praxis Precision Medicine and Schedule 1 Therapeutics and consultancy support from AbbVie. LRG reports recent consultancy support from Teva and research support from the Australian National Health and Medical Research Council and the US Migraine Research Foundation. IdB reports independent support from the International Retinal Research Foundation and Dutch Heart Foundation. AVEH, LSV, OI, NP, NM, HS, and RAL declare no conflict of interest. Ethics approval: The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Human Research Ethics Committee of the Queensland University of Technology (approval number: 1800000611) and by the Medical Ethics Committee of LUMC. Consent to participate: Appropriate consents for the patient cohort, are already in place. Consent for publication: Not applicable
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