CORRELATING RATIOS OF AMINES IN PLASMA AND CEREBROSPINAL FLUID 59 3 in plasma; L-Glutamine was the most abundant amine in CSF (MO: median: 589 mM and interquartile range: 516-637 mM, MA: median: 568 mM and interquartile range: 516-616 mM) with similar concentrations in blood (MO: median: 674 mM and interquartile range: 595-752 mM, MA: median: 653 mM and interquartile range 587-712 mM). Figure 2 Correlation matrix of all possible metabolite ratios Coefficients of determination (R2) of all possible metabolite ratios are plotted in healthy controls. The higher the R2 the brighter the square. Grey squares: ratio not applicable. Single plasma/CSF metabolite correlations Additionally, we assessed single correlations in samples from participants with migraine (Table 7, Table S4). Similar as in healthy controls, most amines had low correlation between plasma and
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