CORRELATING RATIOS OF AMINES IN PLASMA AND CEREBROSPINAL FLUID 63 3 Table 3 Single CSF-plasma correlations for single metabolites in healthy controls Metabolite r R2 95% c.i. FDR Homocitrulline .75 .56 .41 - .68 6.16E-17 S-Methylcysteine .75 .56 .41 - .68 6.16E-17 Methionine sulfone .75 .56 .41 - .68 6.16E-17 L-Alpha-aminobutyric acid .73 .54 .39 - .67 2.71E-16 L-Threonine .69 .48 .32 - .62 5.03E-14 3-Methoxytyrosine .64 .40 .24 - .55 3.11E-11 L-Arginine .57 .32 .17 - .48 1.33E-08 L-Glutamine .47 .22 .09 - .38 5.97E-06 L-Lysine .46 .21 .08 - .37 1.11E-05 L-Serine .46 .21 .08 - .37 1.20E-05 L-Tyrosine .45 .21 .08 - .36 1.37E-05 L-Proline .44 .20 .07 - .35 2.27E-05 Citrulline .44 .19 .07 - .35 2.58E-05 Glycine .43 .18 .06 - .34 4.56E-05 L-Asparagine .42 .17 .05 - .33 6.85E-05 Ethanolamine .41 .17 .05 - .32 9.12E-05 L-Alanine .41 .17 .05 - .32 9.96E-05 N6-N6-N6-Trimethyl-L-lysine .40 .16 .05 - .32 1.04E-04 L-4-hydroxy-L-proline .36 .13 .03 - .28 6.05E-04 L-Isoleucine .35 .12 .03 - .27 8.95E-04 L-Leucine .35 .12 .02 - .26 1.12E-03 Ornithine .34 .12 .02 - .26 1.29E-03 L-Valine .33 .11 .02 - .25 1.70E-03 Gamma-Glutamylglutamine .33 .11 .02 - .25 2.09E-03 Putrescine .32 .10 .02 - .25 2.13E-03 L-2-aminoadipic acid .30 .09 .01 - .23 4.59E-03 L-Pipecolic acid .29 .08 .01 - .21 7.34E-03 L-Histidine .25 .06 .00 - .18 2.31E-02 Taurine .18 .03 .00 - .14 1.01E-01 L-Tryptophan .17 .03 .00 - .13 1.38E-01 L-Homoserine .16 .03 .00 - .13 1.40E-01 L-Methionine .16 .02 .00 - .12 1.59E-01 Gamma-L-glutamyl-L-alanine .15 .02 .00 - .12 1.64E-01 SDMA .12 .01 .00 - .10 2.97E-01 L-Glutamic acid .09 .01 .00 - .08 4.56E-01 L-Phenylalanine .08 .01 .00 - .08 4.56E-01 Gamma-aminobutyric acid .08 .01 .00 - .08 4.80E-01 L-Methionine sulfoxide .06 .00 .00 - .07 5.58E-01 Glutathione .02 .00 .00 - .05 8.63E-01 Metabolites are ranked by value of this coefficient and values ≥ .7 are printed in bold. Table is based on corrected data. r = Pearson correlation coefficient; R2 = coefficient of determination; 95% c.i. = 95% confidence interval of R2; FDR = false discovery rate.
RkJQdWJsaXNoZXIy MTk4NDMw