35 Review Immune Cells in Animal Burn Models Figure 6. Subgroup analysis of immune cell counts after burn injury. Subgroup analysis of (A) burned TBSA, (B) species, (C) burn agent, (D) age, (E) sex, and (F) wound depth. Only subgroups for which at least five articles were available were used in the analysis. Results are shown as SMD of immune cell counts in blood or wound tissue from burn-injured animals compared with immune cell counts in blood or skin from uninjured animals (baseline or control group) ± CI95%. The I 2 statistic, number of studies, and the total number of animals in the burn group for each subgroup are shown below the graphs. Bonferroni-corrected P-values of significant differences between subgroups are given in the graphs. CI95%, 95% confidence interval; FT, full-thickness; PT, partial-thickness; SMD, standardized mean difference; TBSA, total body surface area. 2
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