Henk-Jan Boersema

70 Chapter 4 Table 2 Associations of socio-demographic and disease related variables with the inability to work fulltime (univariable and multivariable logistic regression analyses) (n = 30,138) Univariable analyses Multivariable analyses OR 95% CI p-value OR 95% CI p-value Age (years) 1.01 1.01–1.01 < .001 1.01 1.01–1.01 < .001 Female gender 1.33 1.27–1.40 < .001 1.45 1.37–1.52 < .001 Education level Low (ref) – – – – Middle 1.46 1.39–1.54 < .001 1.33 1.25–1.40 < .001 High 1.83 1.71–1.96 < .001 1.44 1.33–1.55 < .001 Multimorbidity 1.13 1.08–1.18 < .001 1.06 1.01–1.11 0.031 Disease group Infectious and parasitic diseases 6.16 4.37–8.66 < .001 6.10 4.32–8.61 < .001 Neoplasms 8.28 7.40–9.26 < .001 8.12 7.26–9.08 < .001 Diseases of the blood and blood-forming organs 11.42 8.79–14.85 < .001 10.91 8.37–14.21 < .001 Endocrine, nutritional and metabolic disorders 3.12 2.59–3.76 < .001 3.06 2.54–3.70 < .001 Mental and behavioural disorders 2.74 2.56–2.93 < .001 2.70 2.52–2.90 < .001 Diseases of the nervous system 6.04 5.39–6.77 < .001 5.83 5.19–6.54 < .001 Diseases of the eye and adnexa 2.12 1.65–2.72 < .001 2.01 1.56–2.58 < .001 Diseases of the ear and mastoid process 2.70 2.10–3.48 < .001 2.50 1.94–3.23 < .001 Diseases of the circulatory system 6.11 5.54–6.75 < .001 6.37 5.77–7.05 < .001 Diseases of the respiratory system 7.84 6.70–9.18 < .001 8.11 6.92–9.50 < .001 Diseases of the digestive system 6.00 4.93–7.27 < .001 5.87 4.83–7.14 < .001 Diseases of the skin and subcutaneous tissue 1.27 0.86–1.89 .235 1.30 0.87–1.93 .209 Diseases of the musculoskeletal system and connective tissue (ref) – – – – – – Diseases of the genitourinary system 7.37 5.72–9.51 < .001 7.29 5.64–9.41 < .001 Pregnancy, childbirth and the puerperium 1.26 0.84–1.89 .273 1.09 0.72–1.65 .674 Congenital malformations, deformations and chromosomal abnormalities 4.07 2.90–5.71 < .001 4.09 2.90–5.76 < .001 Symptoms, signs and abnormal clinical and laboratory findings 1.55 1.37–1.76 < .001 1.20 1.05–1.37 .009 Injury, poisoning and certain other consequences of external causes 1.42 1.27–1.59 < .001 1.46 1.30–1.63 < .001 OR odds ratio, CI confidence interval, ref reference group

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