71 Inability to work fulltime, prevalence and associated factors Associations of Each Included Disease Group with the Inability to Work Fulltime For each of the included disease groups the population attributable fraction for being assessed with inability to work fulltime, and the association with the inability to work fulltime was studied and compared to the all the other applicants in the study sample not having that specific disease group as the primary diagnosis. Disease groups with the highest population attributable fractions were neoplasms (5.2%) and diseases of the circulatory system (4.6%). Whereas diseases of the musculoskeletal system showed the lowest population attributable fraction (− 19.3%) (Table 3). Univariable analyses showed significantly higher odds ratios for the inability to work fulltime for infectious and parasitic diseases, neoplasms, diseases of the blood and blood-forming organs, endocrine and nutritional and metabolic disorders, mental and behavioural disorders, diseases of the nervous system, the circulatory system, the respiratory system, the digestive system, the genitourinary system, and congenital malformations when compared to the applicants having a disorder of another disease group as the primary disorder. Applicants with diseases of the skin and subcutaneous tissue, the musculoskeletal system, pregnancy, symptoms and signs and abnormal clinical and laboratory findings, and injury and poisoning and certain other consequences of external causes had significantly lower odds ratios. Diseases of the eye and of the ear were not significantly associated with the inability to work fulltime (for odds ratio’s see Table 3). When adjusted for gender, age, educational level and multimorbidity, multivariable analyses showed similar results, except for endocrine disorders, which was not significantly associated anymore, and applicants with diseases of the eye were significantly less likely to have an inability to work fulltime (Table 3). The disease groups with the highest odds ratios for an inability to work fulltime in the multivariable analyses were diseases of the blood and blood forming organs (OR 4.35, 95% CI 3.36–5.65), neoplasms (OR 3.18, 95% CI 2.87–3.53), and diseases of the respiratory system (OR 3.34, 95% CI 2.87–3.89). The disease groups with the lowest odds for an inability to work fulltime were diseases of the musculoskeletal system and connective tissue (OR 0.29, 95% CI 0.27–0.30), pregnancy, childbirth and the puerperium (OR 0.46, 95% CI 0.31–0.69), and symptoms, signs and abnormal clinical and laboratory findings (OR 0.60, 95% CI 0.53–0.67) (Table 3). 4
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