Evert den Drijver

59 Development of an algorithm to discriminate between plasmid- and chromosomal-mediated AmpC Figure 2. Ridge plot of Etest MICs for 172 E. coli strains grouped by genotype. The x-axis indicates MICs in mg/L. The left-hand y-axis indicates genotypes of strains. The right-hand y-axis indicates number of counts for each MIC; counts are scaled for each Etest to enhance visibility. R, resistant; S, susceptible. a MIC cut-off adapted from EUCAST guideline on detection of resistance mechanisms v2.0. b MIC breakpoints according to EUCAST clinical breakpoints for bacteria v.9.0. 4

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