65 Development of an algorithm to discriminate between plasmid- and chromosomal-mediated AmpC Acknowledgements Many thanks to M. Janssens (Laboratory for Medical Microbiology and Immunology, Elisabeth-Tweesteden Hospital, Tilburg, the Netherlands) and S. van Leest (Laboratory for Microbiology, Microvida, location Bravis Hospital, the Netherlands) for providing samples that were included in validation set 1. Many thanks to K. T. Veldman and D. J. Mevius (Department of Bacteriology and Epidemiology, Wageningen Bioveterinary Research, Lelystad, the Netherlands), E. A. Reuland (Medical Microbiology and Infection Control, Amsterdam UMC location VUmc, Amsterdam, the Netherlands) and W. H. F. Goessens (Erasmus University Medical Center, Rotterdam, Netherlands) for providing samples that were included in validation set 2. Many thanks to R. Bosboom (Rijnstate, Arnhem, the Netherlands) and P. Vos (Check-Points, Wageningen, the Netherlands) for providing additional strains. We thank both H. W. Hoogewerf and L. van der Wiel for their input on and discussions about machine learning. Funding This research was partly funded by INTERREG health-i-care consortium 17 (European Union funding programme). Transparency declarations None to declare. 4
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