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91 Detection of AmpC beta-lactamases in E. coli using different screening agars cefotaxime or ceftazidime with cefoxitin do not seem to be inferior in sensitivity compared to agars without cefoxitin, and may be promising when used additional to e.g. a ESBL specific screenings agar for screening of 3rd generation cephalosporin resistance in E. coli. Declarations Funding This research did not receive any specific grant from funding agencies. Competing interests The authors declare no competing interests. Authors’ contributions E.D. and J.A.J.W.K. conceived of and designed the study ; J.S. and C.V. were responsible for laboratory processing of the isolates ; J.J.V. conducted molecular analysis of local strains ; K.V., J.W.R., A.M.D.K.S., and M.F.Q.K. provided isolates for the strain collection and revised and approved the manuscript. E.D. performed the analyses and wrote the first draft of the manuscript with input from J.A.J.W.K. All authors contributed to preparation of the final manuscript. Acknowledgments The authors thank the laboratory technicians from the laboratory for Microbiology and Infection Control of the Amphia Hospital, the Central Veterinary Institute, the Department of Medical Microbiology, University Medical Center Groningen and the Department of Medical Microbiology, Certe involved in the setup of the strain collection. 5

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