113 (Phospho)proteomics biomarkers for sunitinib response in RCC 108 Chen, Z. et al. Prognostic role of pretreatment serum albumin in renal cell carcinoma: a systematic review and meta-analysis. Oncotargets Ther 9, 6701-6709, doi:10.2147/Ott.S108469 (2016). 109 Campbell, L. et al. Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease. J Transl Med 11, doi:Artn 255 10.1186/1479-5876-11-255 (2013). 110 Ellinger, J. et al. Systematic Expression Analysis of Mitochondrial Complex I Identifies NDUFS1 as a Biomarker in Clear-Cell Renal-Cell Carcinoma. Clin Genitourin Canc 15, E551-E562, doi:10.1016/j. clgc.2016.11.010 (2017). 111 Baumunk, D. et al. Expression parameters of the metabolic pathway genes pyruvate dehydrogenase kinase-1 (PDK-1) and DJ-1/PARK7 in renal cell carcinoma (RCC). World J Urol 31, 1191-1196, doi:10.1007/s00345-012-0874-5 (2013). 112 Zhou, W. M. et al. Low expression of PDK1 inhibits renal cell carcinoma cell proliferation, migration, invasion and epithelial mesenchymal transition through inhibition of the PI3K-PDK1-Akt pathway. Cell Signal 56, 1-14, doi:10.1016/j.cellsig.2018.11.016 (2019). 113 Pak, S., Kim, W., Kim, Y., Song, C. & Ahn, H. Dihydrotestosterone promotes kidney cancer cell proliferation by activating the STAT5 pathway via androgen and glucocorticoid receptors. J Cancer Res Clin 145, 2293-2301, doi:10.1007/s00432-019-02993-1 (2019). 114 Sarto, C. et al. Expression of heat shock protein 27 in human renal cell carcinoma. Proteomics 4, 2252-2260, doi:DOI 10.1002/pmic.200300797 (2004). 115 Liu, Y. Y. et al. Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF-beta 1/p38/HSP27 signaling in renal cell carcinoma. Oncotarget 7, 81410-81422, doi:10.18632/oncotarget.12937 (2016). 116 Zhao, Y. B. et al. PTRF/CAVIN1, regulated by SHC1 through the EGFR pathway, is found in urine exosomes as a potential biomarker of ccRCC. Carcinogenesis 41, 274-283, doi:10.1093/carcin/bgz147 (2020). 117 Beraud, C. et al. Targeting FAK scaffold functions inhibits human renal cell carcinoma growth. International Journal of Cancer 137, 1549-1559, doi:10.1002/ijc.29522 (2015). 118 Oka, H. et al. Constitutive Activation of Mitogen-Activated Protein (Map) Kinases in Human Renal-Cell Carcinoma. Cancer Research 55, 4182-4187 (1995). 119 Huang, D. et al. Inhibition of MAPK kinase signaling pathways suppressed renal cell carcinoma growth and angiogenesis in vivo. Cancer Research 68, 81-88, doi:10.1158/0008-5472.Can-07-5311 (2008). 120 Chua, B. T., Lim, S. J., Tham, S. C., Poh, W. J. & Ullrich, A. Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells. Mol Oncol 4, 323-334, doi:10.1016/j.molonc.2010.03.001 (2010). 121 Jenq, W. M., Cooper, D. R. & Ramirez, G. Integrin expression on cell adhesion function and up-regulation of P125(FAK) and paxillin in metastatic renal carcinoma cells. Connective Tissue Research 34, 161-174, doi:Doi 10.3109/03008209609000696 (1996). 4
RkJQdWJsaXNoZXIy MTk4NDMw