122 Chapter 5 Figure 6. SVR-LSM for the semantic fluency. The thresholded lesion overlap for this task is shown for both the tumor (A) and stroke group (B). The color bar indicates the number of patients with overlapping lesions. Voxels that were significantly associated with worse performance are shown for the tumor group (red) and the stroke group (blue) for the semantic fluency (C). The colors indicate the p-value for each voxel. The green outline indicates the area within which both groups had a minimum lesion overlap of 3 patients. L = left, R= right. Specificity of lesion-symptom results Specificity of the lesion-symptom results was assessed by calculating the amount of overlap between voxels that were significantly related to any of the three memory tasks compared to the two fluency tasks. For the tumor group, there was a 2.0% overlap between voxels related to both memory and fluency performance. This overlap was mainly located in and around the left cortico-spinal tract, internal capsule, arcuate fasciculus and corpus callosum. Additionally, some overlapping voxels were found in the left precentral gyrus. 13.9% of voxels associated with all three memory tasks and 33.9% with any two memory tasks. Overlapping areas for all three tasks were located in the left hippocampus, parahippocampal gyrus, the
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