Eva van Grinsven

124 Chapter 5 For the lesion-symptom associations found solely in the stroke group, only the left putamen had sufficient lesion coverage to allow further post-hoc analysis. None of the post-hoc analysis for the left putamen, showed significant main or interaction effects. The variability in cognitive performance was high in the subset of subjects with left putamen lesions, independent of etiology. Figure 7. Post-hoc interaction plots based on SVR-LSM results. Plots show the mean and standard error of the cognitive performance per etiology (tumor [black] versus stroke [white]), and lesion status (lesion versus no lesion). All brain areas were in the left hemisphere and their labels are depicted below the individual plots. Cognitive performance on the different tasks (semantic fluency, letter fluency, direct recall RAVLT and delayed recall RAVLT) is shown as z-scores on the y-axis. An asterisk next to the label indicates a brain area for which a significant interaction effect was found.

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