Eva van Grinsven

Chapter 1 General introduction and thesis outline	7
Part I: Neurocognitive functioning in patients with brain metastases	23
Chapter 2 The impact of stereotactic or whole brain radiotherapy on neurocognitive functioning in adult patients with brain metastases– A systematic review & meta-analysis	25
Chapter 3 Different profiles of neurocognitive functioning in patients with brain metastases prior to brain radiotherapy	57
Chapter 4 Individualized trajectories in post-radiotherapy neurocognitive functioning of patients with brain metastases	79
Part II: Using imaging techniques to understand neurocognitive functioning	103
Chapter 5 The impact of etiology in lesion-symptom mapping – A direct comparison between tumor and stroke	105
Chapter 6 Hemodynamic imaging parameters in brain metastases patients – Agreement between multi-delay ASL and hypercapnic BOLD	145
Chapter 7 Evaluating physiological MRI biomarkers and cognitive performance in patients with brain metastases after stereotactic radiosurgery - a preliminary analysis and case-report	171
Summary and Discussion	201
Chapter 8 Summary	203
Chapter 9 Discussion	211
Chapter 10 Summary in Dutch (Nederlandstalige samenvatting)	235
Appendices	245
List of publications	246
Educational portfolio	250
Dankwoord (Acknowledgements)	252
About the author	262

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