152 6 Chapter 6 Secondary outcomes Clinical outcomes 1. Dyspnoea, as measured by the Medical Research Council (MRC) Dyspnea Scale - Bestall 1999 - or the Borg Scale - Borg 1970 2. Survival (mortality) 3. Lung function (FEV1, FVC) 4. Depression, as measured by the Hospital Anxiety and Depression Scale (HADS) - Zigmond 1983 - or the Beck Depression Inventory (BDI) - Beck 1961 Process-related outcomes 1. Coordination of care (e.g. accessibility of care, rate of patient participation in the disease management programme, patients’ and healthcare professionals’ satisfaction with the programme, extent to which disease management was implemented, from the perspective of the patient (PACIC) - Glasgow 2005) We evaluated outcomes at (1) short-term (up to 6 months), (2) medium-term (6 to 15 months), and (3) long-term (longer than 15 months) endpoints, if possible. Search methods for identification of studies Electronic searches The previously published version of this review included studies up to April 2013. For the current update, we identi ed studies using the Cochrane Airways Group Register of trials; the Cochrane Central Register of Controlled Trials (CENTRAL), in the Cochrane Library; MEDLINE (Ovid SP); Embase (Ovid SP); and the Cumulative Index to Nursing and Allied Health Literature (CINAHL) (EBSCO). We used speci c medical subject headings (from MeSH) and additional keywords to identify all trials on IDM in COPD patients. The search strategy was developed and conducted in collaboration with the Cochrane Airways Information Specialist. The initial strategy was developed for MEDLINE and was adapted for use in the other databases. Complete search strategies for the database searches are provided in the appendices (MEDLINE - Appendix 1; Embase - Appendix 2; CINAHL - Appendix 3; CENTRAL - Appendix 4; Airways Register - Appendix 5). The search period for this update covers April 2013 to September 2020. This includes an initial search on 4 January 2017 and updates in March 2018 and March 2019. We ran a nal update search in September 2020. Searching other resources To identify all possible studies, we carried out an additional search for systematic reviews in the Cochrane Database of Systematic Reviews. We also screened reference lists of included studies and systematic reviews for potential studies for inclusion in the current review. To identify ongoing or new studies, we searched databases of ongoing
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