159 6 Cochrane review on integrated disease management for COPD 26 studies included in previous version of review (Kruis 2013) 10,149 records identified through database searching (2013-2020) 71 records identified through other sources (ClinicalTrials.gov) 6900 records after duplicates removed 6900 records screened 53 records excluded by Cochrane Crowd Known assessments 420 records excluded by RCT Classifier 6070 records excluded on title/abstract 357 full-text articles assessed for eligibility 118 studies (281 records) excluded, with reasons: not an RCT (n=7); no results for COPD patients (n=5); only one healthcare provider of different discipline involved (n=64); only one component intervention (n=14); duration less than 3 months (n=19); active treatment in control group (n=9). 7 studies (7 records) awaiting classification. 11 studies (12 records) ongoing. 26 new studies (57 records) included Figure 1. Study flow diagram
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