176 6 Chapter 6 2.4 Maximal exercise capacity Four studies on 298 participants assessed maximum exercise capacity (in Watts) using the cycle ergometer test (Engstrom 1999; Strijbos 1996; van Wetering 2010; Wijkstra 1994). Pooling showed that IDM statistically signi cantly improved maximal exercise capacity by 7 Watts (MD 6.99, 95% CI 2.96 to 11.02; Analysis 1.17). 3. Exacerbation-related outcomes 3.1 Respiratory-related admissions Fifteen studies including a total of 4207 participants reported on the number of patients with at least one respiratory-related admission, which could be COPD-related, exacerbation-related, or of a respiratory nature in general. Pooling showed an e ect in favour of the IDM intervention (OR 0.64, 95% CI 0.50 to 0.81). In other words, per 1000 patients, 89 fewer (range 131 fewer to 44 fewer) patients had a respiratory-related (re-) hospitalisation compared to patients given usual care (Analysis 1.18; Figure 5). Figure 5. In the usual care group, 32 out of 100 people had a respiratory-related hospital admission over a period of 3 to 36 months, compared to 23 (95% CI 19 to 28) out of 100 people in the integrated disease management group.
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