20 Chapter 1 1 Chapter title Research aim Dissertation aim Design or research method Design or research phase Deliverable stakeholders involved Part 2 - Effectiveness Assessment 5. Protocol for a cluster RCT on a smart asthma inhaler programme To investigate the effectiveness of a smart inhaler asthma self-management programme on medication adherence and clinical outcomes in adults with uncontrolled asthma, to evaluate its acceptability, and to identify subgroups who would benefit most based on patient characteristics. To illustrate collection of long-term real-world evidence of a complex eHealth intervention within a cluster RCT. To provide an approach on how to identify which patients benefit most, based on patient characteristics. To illustrate patient participation in the design and execution of a RCT. Cluster RCT, pragmatic trial, patient involvement. Protocol for an effectiveness evaluation. Protocol for the evaluation of the effectiveness and cost-effectiveness of a smart asthma inhaler programme in primary care in the Netherlands. Smart inhaler developers, patient advocates. 6. Cochrane review update To compare the effectiveness of integrated disease management (IDM) programmes versus usual care for people with COPD on various clinical outcomes. To shed light on the methodological challenges of complex health interventions, such as eHealth and the importance of contextual factors. Systematic review, meta- analysis, Risk of Bias Grading, GRADE approach. Synthesis and appraisal of all empirical evidence. Various (eHealth and non- eHealth based) complex health interventions.
RkJQdWJsaXNoZXIy MTk4NDMw