CHAPTER 4 100 15 PTEN:c.635-16_636del p.(?) 55 88 4 15 TP53:c.537T>G p.(His179Gln) 80 86 4 15 Microsatellite stable 17EEC ARID1A:c.3219G>A p.(Try1073*) 17 24 4 17EEC AKT1:c.49G>A p.(Glu17Lys) 22 50 5 17EEC TP53:c.817C>T p.(Arg273Cys) 61 289 4 17CC TP53:c.817C>T p.(Arg273Cys) 61 289 4 17CC ARIDA1:c.3826C>T p.(Arg1276*) 22 14 4 17CC ERBB2:c.2524G>A p.(Val842Ile) 39 142 5 17CC MTOR:c.5395G>A p.(Glu1799Lys) 41 966 5 17 Microsatellite instable 18 No (potentially) pathogenic variants Microsatellite stable 19 PIK3CA:c.1636C>A p.(Gln546Lys) 19 669 5 19 PIK3CA:c.1035T>A p.(Asn345Lys) 52 48 5 19 POLE:c.857C>G p.(Pro286Arg) 36 566 5 19 PTEN:c.1021T>G p.(Phe341Val) 63 376 5 19 MTOR:c.6644C>A p.(Ser2215Tyr) 42 196 5 19 MTOR:c.7513C>T p.(Arg2505*) 28 248 5 19 TP53:c.339C>A p.(Phe113Leu) 16 381 5 19 Microsatellite stable 20 ARID1A:c.2808del p.(Ser936fs) 39 56 4 20 PIK3CA:c.3140A>G p.(His1047Arg) 21 22 5 20 TP53:c.338T>G p.(Phe113Cys) 16 43 5 20 Microsatellite stable 21 ARID1A:c.6420del p.(Phe2141fs) 30 128 4 21 KRAS:c.34G>T p.(Gly12Cys) 18 96 5 21 PTEN:c.437dup p.(Leu146fs) 32 426 4 21 PIK3CA:c.278G>T p.(Arg93Leu) 26 42 4 21 Microsatellite instable 27 KRAS:c.35G>A p.(Gly12Asp) 47 30 5 27 PTEN:c.800del p.(Lys267fs) 35 22 4 27 Microsatellite instable 29 TP53:c.406C>T p.(Gln136*) 5 10 4 29 ARIDA1:c.3826C>T p.(Arg1276*) 6,8 10 4 29 Microsatellite stable 31 No (potentially) pathogenic variants Microsatellite stable Supplementary C. Continued
RkJQdWJsaXNoZXIy MTk4NDMw