ABNORMAL HAEMATOLOGICAL PARAMETERS IN EC 163 7 Total number of patients of the included cohorts: PIPENDO cohort: 432 patients UK cohort: 514 patients Excluded based on: Non of the three hematological parameters were present PIPENDO cohort: 26 patients UK cohort: 24 patients 896 patients Excluded based on: Abnormally high leukocyte count PIPENDO cohort: 2 patients UK: 0 patients Total number of patients included in this study: 894 patients Figure 1. Study flowchart Statistical analysis The haematological parameters were analysed as a dichotomous value, with defined cutoffs. Anaemia was defined according to the World Health Organization as haemoglobin level <7.45mmol/L (<12g/Dl)29, thrombocytosis as platelet counts >400x109 /L according multiple studies involving gynaecologic malignancies13, and leucocytosis as leukocyte counts >10x109/L.15 The risk classification groups were classified according to the ESGO/ESTRO/ESP guideline; low, intermediate, high-intermediate, high and advanced/metastatic risk group.7 To explore the response on RT, all patients who received solely adjuvant RT were included for the
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