Stephanie Vrede

AMOUNT OF PREOPERATIVE ENDOMETRIAL TISSUE 33 2 Table 1. Baseline characteristics Total (n=573) Postoperative Low-grade (n=462) Postoperative High-grade (n=111) P Age (years) 64.8 ± 9.8 64.1 ± 9.6 66.6 ± 10.0 0.014* BMI (kg/m2) 30.2 ± 6.7 30.4 ± 6.5 28.7 ± 5.5 0.013* Preoperative grade Premalignant† 8 (1.4) 8 (1.7) 0 (0.0) <0.001* 1 EEC 308 (53.8) 295 (63.9) 13 (11.7) 2 EEC 156 (27.2) 132 (28.6) 24 (21.6) 3 EEC 74 (12.9) 22 (4.8) 52 (46.8) NEEC 27 (4.7) 5 (1.1) 22 (19.8) Preoperative sampling method Pipelle 259 (45.2) 199 (43.1) 60 (54.1) 0.002* D&C 77 (13.4) 63 (13.6) 14 (12.6) Hysteroscopic biopsy 213 (37.2) 189 (40.9) 24 (21.6) Not specified 24 (4.2) 11 (2.4) 13 (11.7) FIGO stage I 475 (82.9) 413 (89.4) 62 (55.9) <0.001* II 36 (6.3) 24 (5.2) 12 (10.8) III 45 (7.9) 22 (4.8) 23 (20.7) IV 17 (2.9) 3 (0.6) 14 (12.6) Positive nodes No 299 (52.2) 240 (52.0) 59 (53.2) <0.001* Pelvic 17 (3.0) 7 (1.5) 10 (9.0) Para-aortic 11 (1.9) 2 (0.4) 9 (8.1) Both 5 (0.9) 1 (0.2) 4 (3.6) Not specified 241 (42.0) 212 (45.9) 29 (26.1) Adjuvant treatment No 267 (46.7) 238 (51.5) 29 (26.1) <0.001* Radiotherapy 263 (46.0) 204 (44.2) 59 (53.2) Chemotherapy 17 (3.0) 5 (1.1) 12 (10.8) Chemoradiotherapy 25 (4.4) 14 (3.0) 11 (9.9) Missing 1 (0.2) 1 (0.2) Data is presented in number (%), mean ± standard deviation (SD) Abbreviations: EEC, endometrioid endometrial cancer; NEEC, non-endometroid endometrial cancer; BMI, Body Mass Index; FIGO, International Federation of Gynecology and Obstetrics * P<0.05 †including simple or complex hyperplasia, with or without atypia.

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