AMOUNT OF PREOPERATIVE ENDOMETRIAL TISSUE 35 2 Median endometrial tissue surface and degree of concordance An overview of the median endometrial tissue surface related to pre- vs. postoperative tumor grade and histological subtype is shown in Table 2. There was no significant difference between the median endometrial tissue surface of the individual tumor grade and histological subtype preoperatively, nor postoperatively, (P=0.063 and P=0.888, respectively). The median endometrial tissue surface between concordant (dark green) and discordant (light green + red) individual tumor grade and histological subtype showed no significant difference (19.6 mm2 vs. 18.6mm2, respectively, P=0.468). For the clinically relevant low- and high-grade classification, the median endometrial tissue surface for concordant diagnoses (dark green + light green) was significant lower compared to the discordant diagnoses (red) (18.7 mm2 vs. 23.5 mm2, respectively, P=0.022) (Table 2). In Supplementary Table S2 the correlation between median endometrial tissue and concordant and discordant diagnoses is shown per included center. Patients with concordant pre- and postoperative low-grade EC showed lower median endometrial tissue surface compared to preoperative low-grade and postoperative highgrade EC (upgraded), but not significantly (18.4 vs 20.1 mm2, P=0.335). Patients with concordant pre- and postoperative high-grade EC had significant lower endometrial tissue surface compared to patients with preoperative high-grade and postoperative low-grade EC (downgraded) (20.3 vs 38.6 mm2, P=0.044) (Figure 2). B. A. Figure 2 A-B. A. Patients with preoperative low-grade endometrial cancer (EC) and the median endometrial tissue surface for postoperative discordant or concordant diagnoses. B. Patients with preoperative high-grade EC and the median endometrial tissue surface for postoperative discordant or concordant diagnoses.
RkJQdWJsaXNoZXIy MTk4NDMw