MOLECULAR PROFILING IN LOW-GRADE EC 67 3 Chemotherapy 9 (3.4) 1 (2.4) 14 (50.0) 5 (17.9) 4 (13.3) Chemoradiation 27 (10.2) 1 (2.4) 2 (7.1) 2 (7.1) 2 (6.7) Unknown 0 (0.0) 3 (7.1) 1 (3.6) 0 (0.0) 0 (0.0) Mortality Recurrence 34 (12.8) 13 (31.0) 9 (32.1) 12 (42.9) 6 (20.0) Mortality 40 (15.1) 11 (26.2) 12 (42.9) 14 (50.0) 13 (43.3) EC-related mortality 29 (10.9) 9 (21.4) 9 (32.1) 13 (46.4) 13 (43.3) Data is presented as No. (%), median (IQR) Abbreviations: POLE, Polymerase epsilon; MSI, Microsatellite instability; TP53, Tumor protein 53; NSMP, No-specific molecular profile; EEC, endometrioid endometrial cancer; NEEC, non-endometrioid endometrial cancer; MI, myometrial invasion; LVSI, lymphovascular space invasion; N0, negative lymph nodes, N1, positive lymph nodes; Nx, no information about the lymph nodes; FIGO, Federation International of Gynecology and Obstetrics; EBRT, external beam radition therapy; VBT, vaginal brachytherapy; EC, endometrial cancer.
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