Stephanie Vrede

TABLE OF CONTENTS Chapter 1 General introduction and outline thesis Chapter 2 The amount of preoperative endometrial tissue surface in relation to final endometrial cancer classification; Gynecologic Oncology 2022 Chapter 3 Relevance of molecular profiling in patients with low-grade endometrial cancer; Jama Network Open 2022 Chapter 4 Pure and mixed clear cell carcinoma of the endometrium: A molecular and immunohistochemical analysis study; Cancer Medicine 2023 Chapter 5 Immunohistochemical biomarkers are prognostic relevant in addition to the ESMO-ESGO-ESTRO risk classification in endometrial cancer; Gynecologic Oncology 2021 Chapter 6 Hormonal biomarkers remain prognostically relevant within the molecular subgroups in endometrial cancer; submitted Chapter 7 Abnormal preoperative haematological parameters in endometrial cancer; worse prognosis reflecting tumour aggressiveness or reduced response to radiotherapy?; Journal of Obstetrics and Gynaecology 2024 Chapter 8 General discussion Chapter 9 Summary / Samenvatting Appendix Research Data Management PhD Portfolio Curriculum Vitae List of publications Dankwoord 9 27 49 77 109 135 159 181 201 213 215 217 219 223

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