265 Generation of Human iPSC lines derived from PLN R14del Cardiomyopathy Patients 10 2. Resource Table 1 Unique stem cell lines identifier UMCUi001-A, UMCUi002-A, UMCUi003-A, UMCUi003-B, UMCUi003-C, UMCUi004-A, UMCUi005-A, UMCUi006-A, UMCUi006-B, UMCUi006-C, UMCUi007-A, UMCUi007-B, UMCUi008-A, UMCUi008-B. Alternative name(s) of stem cell lines PLN-R14del-2AC3 (UMCUi001-A) PLN-R14del-3AC7 (UMCUi002-A) PLN-R14del-6BC2 (UMCUi003-A) PLN-R14del-6BC7 (UMCUi003-B) PLN-R14del-6BC13 (UMCUi003-C) PLN-R14del-7AC13 (UMCUi004-A) PLN-R14del-10AC21 (UMCUi005-A) PLN-R14del-10BC12 (UMCUi006-A) PLN-R14del-10BC13 (UMCUi006-B) PLN-R14del-10BC15 (UMCUi006-C) PLN-1CC2 (UMCUi007-A) PLN-1CC6 (UMCUi007-B) PLN-5AC1 (UMCUi008-A) PLN-5AC2 (UMCUi008-B) Institution Utrecht Regenerative Medicine Center, Circulatory Health Laboratory, University Utrecht, Department of Cardiology, Experimental Cardiology Laboratory, University Medical Center Utrecht, 3508 GA Utrecht, the Netherlands Contact information of distributor Joost Sluijter, j.sluijter@umcutrecht.nl Type of cell lines iPSC Origin Human Additional origin info PLNR14del carriers: UMCUi001-A, Age: 25, Sex: M, UMCUi002-A, Age: 31, Sex: F, UMCUi003-A/UMCUi003-B/UMCUi003-C, Age: 65, Sex: M, UMCUi004-A, Age: 63, Sex: F, UMCUi005-A, Age: 66, Sex: F, UMCUi006-A/UMCUi006-B/UMCUi006-C, Age: 64, Sex: F. Healthy proband donors: UMCUi007-A/UMCUi007-B, Age: 67, Sex: M, UMCUi008-A/ UMCUi008-B, Age: 44, Sex: M. Cell Source Total PBMCs Clonality Clonal Method of reprogramming Sendai virus reprogramming (OCT4, SOX2, KLF4, and c-MYC) Genetic Modification Yes Type of Genetic Modification Hereditary Evidence of the reprogramming transgene loss Taqman (Kit) Associated disease Dilated and arrhythmogenic cardiomyopathies Gene/locus PLN/6q22.31 c.40_42delAGA (p.Arg14del) Date archived/stock date 11/03/2021 Ethical approval Medical Ethical Committee (TCBio) of University Medical Center (UMC) Utrecht; approval number: 12–387
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