38 Chapter 2 Table 1: Description of the included studies First Author (Year/ Country) Aim Of The Study Study Design Sample Size Study Population Sex (% Males) Simple Analysis* Advanced Analysis** Purohit, S D (1984 / India) To assess the effect of rifampicin therapy on glucose tolerance Prospective cohort 57 TB patients 77 Yes No Singh, M.M (1984 / India) To determine the prevalence of impaired glucose tolerance in active pulmonary TB patients and to determine the effect of anti-tuberculous chemotherapy on the glucose tolerance curves Prospective cohort 52 TB patients 65 Yes No Oluboyo, P.O (1990 / Nigeria) To determine the significance of glucose intolerance in TB Case-control study 54 Pulmonary TB patients 63 Yes No Jawad, F (1995 / Pakistan) To unmask glucose intolerance in patients with active pulmonary TB and to assess the effect of treatment on its reversal Crosssectional and prospective cohort 106 Outpatient pulmonary TB patients 59 No No Basoglu, O.K (1999 / Turkey) To compare glucose tolerance test results of pulmonary TB patients with those of patients with community-acquired pneumonia Case-control study 58 Pulmonary TB patients 78 Yes No Tarbasi, P (2014 / Iran) To examine HbA1c of new TB patients and relate to if they complete TB treatment Prospective cohort 158 New TB patients 49 Yes No Akinlade, K.S (2016 / Nigeria) To assess changes in glycated haemoglobin levels in MDR-TB patients Longitudinal study 21 MDR-TB patients 68 Yes No Boillat-Blanco, N (2016 / Tanzania) To examine the association of TB and its outcome with the presence and persistence of hyperglycaemia in Tanzania, using three different DM screening tests. Case-control study 530 Pulmonary TB patients 58 Yes Yes Lin, Y (2017 / China) To understand if blood glucose levels were stable or fluctuated during TB treatment Prospective cohort 270 TB patients 66 Yes Yes Moreira, J (2018 / Brazil) To assess the impact/prevalence of hyperglycaemia on TB outcomes, comparison of treatment outcomes & one-year mortality rate based on the glycaemic status of patients during treatment Retrospective cohort 473 HIV-TB coinfected patients 69 Yes Yes
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