58 Chapter 2 Colorectal cancer screening programme Reference Study design Number of participants (n) Participants, collection period, region Characteristics Outcomes I-Change model (ToesZoutendijk, van Leerdam et al. 2017) Ref: 43 Retrospective observational cohort study Monitoring of the newly nationally enrolled cancer screening programme. 741,941 Target population 2014. Males and females reaching age of 63, 65, 57 or 75 years. The Netherlands. Sex Age 71.3% A few months into the program it appeared that participation and positive test results were higher than predicted. The positive predictive value was lower than predicted. To reduce the burden of unnecessary colonoscopies and improve colonoscopy capacity, the cut off level for a positive FIT was increased. Close monitoring of the implementation of the program allowed for rapid adjustment. Information factors Motivational factors
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