120 Chapter 4 Supplementary Figure 2. Effect of PPAR-α agonists on peroxisomal biogenesis. (A) Relative gene expression of different peroxisomal biogenesis markers. Organoids were grown in complete culture medium (Control) or in starvation medium for 96 h (Starved), starvation medium with vehicle (DMSO) and (BSA) and in the presence of two different concentrations of WY-14643 (100 µM and 200 µM), DHA (50 µM and 100 µM) and LA (50 µM and 150 µM). Data represent mean ± SEM from 3 biological replicates (biological replicates are obtained from independent experiments).
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