164 Chapter 5 Supplementary Table 2. Metabolites at steady state in control, amino-acid restriction and amino-acid restriction supplemented with 100 µM DHA. Supplementary Table 2. Metabolites at steady state in control, amino-acid restriction and amino-acid restriction supplemented with 100 µM DHA. L009 % L011 % L014 % Control DMSO 100DHA Control DMSO 100DHA Control DMSO 100DHA C18 acylcoa 150 150 100 150 100 150 150 100 150 100 150 150 100 150 100 C18enoylcoa 90.669 40.507 44.67568849 76.434 84.3000364 89.065 39.076 43.873575 120.206 134.9643519 118.68 83.414 70.28479946 132.895 111.9776 C18 ketoacyl coa 0.899 0.403 44.82758621 0.759 84.42714127 0.883 0.389 44.05436 1.188 134.5413364 1.173 0.827 70.5029838 1.312 111.85 C16 acylcoa 117.812 117.813 100.0008488 117.812 100 117.812 117.812 100 117.812 100 117.812 117.812 100 117.812 100 C16 acylcarnitine 841.518 841.518 100 841.518 100 841.518 841.518 100 841.518 100 841.518 841.518 100 841.518 100 C16enoylcoa 8.293 3.693 44.53153262 6.979 84.15531171 8.145 3.563 43.744629 11.041 135.5555556 10.898 7.623 69.94861442 12.229 112.2133 C16 ketoacyl coa 0.081 0.036 44.44444444 0.068 83.95061728 0.079 0.035 44.303797 0.107 135.443038 0.105 0.074 70.47619048 0.118 112.381 C14 acylcoa 107.102 107.102 100 107.102 100 107.102 107.102 100 107.102 100 107.102 107.102 100 107.102 100 C14 acylcarnitine 765.016 765.016 100 765.016 100 765.016 765.016 100 765.016 100 765.016 765.016 100 765.016 100 C14enoylcoa 3.889 1.785 45.89868861 3.285 84.46901517 3.82 1.726 45.183246 5.159 135.052356 5.093 3.58 70.29255841 5.713 112.1736 C14ketoacyl coa 0.037 0.018 48.64864865 0.032 86.48648649 0.037 0.017 45.945946 0.049 132.4324324 0.048 0.034 70.83333333 0.054 112.5 C12 acylcoa 347.451 347.451 100 347.451 100 347.451 347.451 100 347.451 100 347.451 347.451 100 347.451 100 C12acylcarnitine 2481.79 2481.79 100 2481.79 100 2481.79 2481.79 100 2481.79 100 2481.79 2481.79 100 2481.79 100 C12enoylcoa 3.343 1.509 45.13909662 2.816 84.23571642 3.283 1.458 44.4106 4.452 135.6076759 4.394 3.074 69.95903505 4.935 112.3122 C12ketoacyl coa 0.032 0.015 46.875 0.027 84.375 0.031 0.014 45.16129 0.042 135.483871 0.042 0.03 71.42857143 0.046 109.5238 C10 acylcoa 191.627 191.627 100 191.627 100 191.627 191.627 100 191.627 100 191.627 191.627 100 191.627 100 C10acylcarnitine 1368.767 1368.767 100 1368.767 100 1368.767 1368.767 100 1368.767 100 1368.767 1368.767 100 1368.767 100 C10enoylcoa 6.145 2.869 46.68836452 5.211 84.80065094 6.04 2.776 45.960265 8.097 134.0562914 7.995 5.668 70.89430894 8.94 111.8199 C10ketoacyl coa 0.06 0.028 46.66666667 0.051 85 0.059 0.027 45.762712 0.079 133.8983051 0.078 0.056 71.79487179 0.087 111.5385 C8acylcoa 649.117 649.117 100 649.117 100 649.117 649.117 100 649.117 100 649.117 649.117 100 649.117 100 C8acylcarnitine 4636.549 4636.549 100 4636.549 100 4636.549 4636.549 100 4636.549 100 4636.549 4636.549 100 4636.549 100 C8enoylcoa 7.345 3.256 44.32947583 6.179 84.12525528 7.213 3.14 43.532511 9.779 135.5746569 9.653 6.75 69.92644774 10.831 112.2035 C8ketoacyl coa 0.072 0.032 44.44444444 0.061 84.72222222 0.071 0.031 43.661972 0.095 133.8028169 0.094 0.066 70.21276596 0.105 111.7021 C6acylcoa 4.46 1.999 44.8206278 3.703 83.02690583 4.29 1.958 45.641026 5.981 139.4172494 5.872 4.136 70.4359673 6.511 110.8822 H2O2 10.308008 4.769578 46.27060825 5.551723 53.85834974 6.907884 5.301351 76.743486 11.62568 168.2958197 11.952325 8.753823 73.23949943 12.11016 101.3205 Flux 0.000144661 6.50E-05 44.92888872 0.000122158 84.44455505 0.000142 6.27E-05 44.116939 1.91E-04 134.448117 0.000188709 1.33E-04 70.58360633 2.11E-04 111.7872
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