José Manuel Horcas Nieto

This work was supported by the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 812968 (PeRIco), the Canadian Institutes of Health Research (156307), the Stichting De Cock-Hadders and Vrienden Beatrix Kinderziekenhuis. The research presented in this thesis was conducted at the Department of Pediatrics, Center for Liver and Metabolic Diseases, University Medical Center Groningen, the Netherlands. The printing of this thesis was financially supported by University of Groningen and the Graduate School of Medical Science of the University Medical Center Groningen. Printing: Ridderprint, ridderprint.nl Layout and design: Ridderprint | www.ridderprint.com © Copyright 2024 Jose Manuel Horcas Nieto, Groningen, The Netherlands. All rights reserved. No part of this thesis may be reproduced, distributed, sorted in a retrieval system, or transmitted in any form o by any means without prior permission of the author or, where applicable, the publisher holding the copyright on the published articles.

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