José Manuel Horcas Nieto

215 7 General Discussion 37. Gan, Z., Qin, X., Liu, H., Liu, J. & Qin, J. Recent advances in defined hydrogels in organoid research. Bioact Mater 28, 386–401 (2023). 38. Kozlowski, M. T., Crook, C. J. & Ku, H. T. Towards organoid culture without Matrigel. Commun Biol 4, (2021). 39. Kamp, F., Zakim, D., Zhang, F., Noy, N. & James Hamilton, and A. Fatty Acid Flip-Flop in Phospholipid Bilayers is Extremely Fast. Biochemistry vol. 34 https://pubs.acs.org/ sharingguidelines (1192). 40. Fitzgerald, G. A., Mulligan, C. & Mindell, J. A. A general method for determining secondary active transporter substrate stoichiometry. Elife 6, (2017). 41. Deori, N. M., Kale, A., Maurya, P. K. & Nagotu, S. Peroxisomes: role in cellular ageing and age related disorders. Biogerontology vol. 19 303–324 Preprint at https://doi. org/10.1007/s10522-018-9761-9 (2018). 42. Di Cara, F., Savary, S., Kovacs, W. J., Kim, P. & Rachubinski, R. A. The peroxisome: an up-and-coming organelle in immunometabolism. Trends in Cell Biology vol. 33 70–86 Preprint at https://doi.org/10.1016/j.tcb.2022.06.001 (2023). 43. Eun, S. Y. et al. PEX5 regulates autophagy via the mTORC1-TFEB axis during starvation. Exp Mol Med 50, (2018). 44. Doherty, J. F., Golden, M. H. & Brooks, S. E. Peroxisomes and the fatty liver of malnutrition: an hypothesis. Am J Clin Nuir 54, 674–681 (1991). 45. Ghislat, G. & Knecht, E. Regulation of Autophagy by Amino Acid Starvation Involving Ca2+. in Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging vol. 6 69–79 (Elsevier Inc., 2015). 46. Chen, R. et al. The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvation. Journal of Cell Biology 206, 173–182 (2014). 47. Derks, T. G. J. et al. The natural history of medium-chain acyl CoA dehydrogenase deficiency in the Netherlands: Clinical presentation and outcome. Journal of Pediatrics 148, (2006).

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