48 Chapter 2 Table 2: An overview of the methodological quality assessment of the RCTs according to the Revised Cochrane risk-of-bias tool for randomized trials (RoB-2) Studies Bias in randomization process Deviations from intended interventions Missing outcome data Bias in outcome measurements Bias in reported results Overall risk of bias Pooni 2022 High Some concerns Low Low Low High Anpalagan 2022 * Low Low NA NA NA NA Diehl 2022 * Low Low NA NA NA NA Valk 2022 * Some concerns Low NA NA NA NA Mangieri 2019 Low Low Low Low Low Low Sysko 2022 Low Low Low Low Some concerns Some concerns Bonn 2020 * Low Low NA NA NA NA Van der Meij 2018 Low Low Low Low Low Low Mata 2020 Low Low Low Low Low Low Rauwerdink 2019 * Low Low NA NA NA NA Doğan 2022 Some concerns Some concerns Low Some concerns Low Some concerns Moon 2021 * Low Low NA NA NA NA Gaj 2017 Low Low Low Some concerns Low Some concerns Smits 2022 Low Low Low Low Low Low * Study protocols for which the methodological quality could not be fully assessed. Abbreviation: NA: not applicable
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