Sara Russo

126 Chapter 4 AUTHOR CONTRIBUTIONS GFV, MK, and BNM conceived and designed the study. GFV, SR and AAAO performed the experiments. PvR advised on collagen topography assessments. MK and AB did the proteome analysis. RB and NG advised on proteome analysis. GFV, SR, BNM, MK, AB, AAAO, and AMD analyzed data and all authors interpreted data. GFV and SR wrote the initial draft of the manuscript. All authors critically reviewed the manuscript and approved the final manuscript. ACKNOWLEDGMENTS Dr. G. Fejer (Plymouth University) is kindly acknowledged for supplying MPI macrophages. FUNDING SOURCES GFV was funded by the Graduate School of Medical Sciences of the University Medical Center Groningen. RB and SR received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No 754425 called Prominent. In addition, ERS/EU RESPIRE 3 also funded parts of the study related to the work of MK. ADDITIONAL INFORMATION PvR is co-founder, scientific advisor, and shareholder of BiomACS BV, a biomedicaloriented screening company. BNM has received research funding from Boehringer Ingelheim outside the scope of this study. All other authors have no conflicts of interest to declare. DATA AVAILABILITY STATEMENT The raw data supporting the conclusion of this article will be made available by the authors upon reasonable request, without undue reservation.

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