132 Chapter 4 Supplementary Table 1. Morphology-independent effects of collagen type I on macrophage protein expression. 77 proteins were differentially expressed by macrophages cultured on collagen type I-coated plastic compared to the uncoated control. Statistically tested with an unpaired Wilcoxon test. p<0.025 was considered significant. Gene name Protein name Fold change p-value Serpinf1 Pigment epithelium-derived factor 35.82 4.74E-03 Fam118b Protein FAM118B 13.21 2.45E-02 Gbp4 Guanylate-binding protein 4 10.34 6.90E-03 Ndrg1 Protein NDRG1 6.22 4.74E-03 Syap1 Synapse-associated protein 1 6.02 2.45E-02 Nudt9 ADP-ribose pyrophosphatase, mitochondrial 5.95 1.35E-02 Golt1b Vesicle transport protein GOT1B 5.27 2.05E-03 Sptlc1 Serine palmitoyltransferase 1 5.18 3.23E-03 Arfgap3 ADP-ribosylation factor GTPase-activating protein 3 5.02 6.90E-03 Thop1 Thimet oligopeptidase 4.93 9.70E-03 Slain2 SLAIN motif-containing protein 2 4.49 6.90E-03 Ethe1 Persulfide dioxygenase ETHE1, mitochondrial 4.14 1.35E-02 Mrps14 28S ribosomal protein S14, mitochondrial 3.95 1.82E-02 Trmt2a tRNA (uracil-5-)-methyltransferase homolog A 3.37 3.23E-03 Eml2 Echinoderm microtubule-associated protein-like 2 3.19 6.90E-03 Alox5 Polyunsaturated fatty acid 5-lipoxygenase 3.19 4.74E-03 Ftl1 Ferritin light chain 1 3.11 1.82E-02 Ctnnd1 Catenin delta-1 2.52 1.82E-02 Nelfa Negative elongation factor A 2.45 9.70E-03 Pfkl ATP-dependent 6-phosphofructokinase, liver type 2.38 9.70E-03 Esyt2 Extended synaptotagmin-2 2.35 6.90E-03 Grhpr Glyoxylate reductase/hydroxypyruvate reductase 2.34 3.23E-03 Acad8 Isobutyryl-CoA dehydrogenase, mitochondrial 2.26 2.45E-02 Tm9sf3 Transmembrane 9 superfamily member 3 2.18 2.45E-02 Fam162a Protein FAM162A 2.12 1.82E-02 Agpat4 1-acyl-sn-glycerol-3-phosphate acyltransferase delta 2.11 2.45E-02 Armc10 Armadillo repeat-containing protein 10 2.10 6.90E-03 F13a1 Coagulation factor XIII A chain 2.06 1.82E-02 Ero1a ERO1-like protein alpha 2.04 9.70E-03 Lrp1 Prolow-density lipoprotein receptor-related protein 1 2.01 4.31E-04 Nnt NAD(P) transhydrogenase, mitochondrial 1.90 1.82E-02 Pcbd2 Pterin-4-alpha-carbinolamine dehydratase 2 1.90 9.70E-03 Spcs2 Signal peptidase complex subunit 2 1.89 6.90E-03 Dhrs7 Dehydrogenase/reductase SDR family member 7 1.86 1.82E-02 Afg3l2 AFG3-like protein 2 1.80 2.45E-02 Basp1 Brain acid soluble protein 1 1.77 1.82E-02 Acot9 Acyl-coenzyme A thioesterase 9, mitochondrial 1.76 1.35E-02 Tpm4 Tropomyosin alpha-4 chain 1.75 1.35E-02 Gsn Gelsolin 1.67 2.45E-02 Pgm1 Phosphoglucomutase-1 1.67 2.45E-02 Bcl10 B-cell lymphoma/leukemia 10 1.65 2.45E-02 Actn4 Alpha-actinin-4 1.64 2.45E-02 Atp5f1e ATP synthase subunit epsilon, mitochondrial 1.61 9.70E-03
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